Bernert, R. A., Hilberg, A. M., Melia, R., Kim, J. P., Shah, N. H., Abnousi, F. Comparative safety and effectiveness of alendronate versus raloxifene in women with osteoporosis. Mitra, M., Shah, N., Mueller, L., Pin, S., Fedoroff, N. School of Earth, Energy and Environmental Sciences, Freeman Spogli Institute for International Studies, Institute for Computational and Mathematical Engineering (ICME), Institute for Stem Cell Biology and Regenerative Medicine, Stanford Institute for Economic Policy Research (SIEPR), Stanford Woods Institute for the Environment, Office of VP for University Human Resources, Office of Vice President for Business Affairs and Chief Financial Officer, Medicine - Biomedical Informatics Research, DOI 10.1146/annurev-biodatasci-080917-013315. Development and utility assessment of a machine learning bloodstream infection classifier in pediatric patients receiving cancer treatments. Huang, S. H., LePendu, P., Iyer, S. V., Tai-Seale, M., Carrell, D., Shah, N. H. Toward personalizing treatment for depression: predicting diagnosis and severity. LePendu, P., Noy, N. F., Jonquet, C., Alexander, P. R., Shah, N. H., Musen, M. A. Nikfarjam, A., Ransohoff, J. D., Callahan, A., Jones, E., Loew, B., Kwong, B. Y., Sarin, K. Y., Shah, N. H. It is time to learn from patients like mine. Callahan, Alison, Igor Pernek, Gregor Stiglic, Jure Leskovec, Howard R. Strasberg and Nigam H. Shah. Learning Effective Treatment Pathways for Type-2 Diabetes from a clinical data warehouse. An important goal of the health system is to identify new adverse drug events (ADEs) in the postapproval period. Response to "Logistic regression in signal detection: another piece added to the puzzle". View details for Web of Science ID 000250355600019, View details for Web of Science ID 000266369400009. Interestingly, NE's growth-suppressive effect is modulated by endogenously expressed catecholamine-inactivating enzymes (COMT and MAO) and is dominant over the growth-promoting effects of PDE-Is. Our user interface enables scientists to search the multiple resources quickly and efficiently using domain terms, without even being aware that there is semantics "under the hood. 0
View details for Web of Science ID 000275419900014, View details for DOI 10.1186/2041-1480-1-S1-I1, View details for Web of Science ID 000297613200031. Nigam has 3 jobs listed on their profile. Just as scientists can ask "Which biological process is over-represented in my set of interesting genes or proteins?" 4/17/2007 Nigam Shah 1060 Continentals way, Apt 408 Belmont, CA 94002 (650) 598-9531 EDUCATION 2005 Ph.D. Integrative Biosciences (IBIOS) The Pennsylvania State University, University Park, PA Unfortunately, the very success of this approach has led to a proliferation of ontologies, which itself creates obstacles to integration.
Our analysis clearly reveals elevated risks for myocardial infarction in rheumatoid arthritis patients taking Vioxx (odds ratio 2.06) before 2005.Our results show that it is possible to apply annotation analysis methods for testing hypotheses about drug safety using electronic medical records. HyQue features a knowledge model to accommodate diverse hypotheses structured as events and represented using Semantic Web languages (RDF/OWL). View details for PubMedCentralID PMC4322575, View details for DOI 10.1186/1546-0096-11-45, View details for Web of Science ID 000328822300001, View details for Web of Science ID 000328251900020, View details for DOI 10.1136/amiajnl-2013-001933. This paper presents the Open Biomedical Annotator (OBA), an ontology-based Web service that annotates public datasets with biomedical ontology concepts based on their textual metadata (www.bioontology.org). Bringing cohort studies to the bedside: framework for a "green button' to support clinical decision-making. Kim, Y., Tian, Y., Yang, J., Huser, V., Jin, P., Lambert, C. G., Park, H., You, S. C., Park, R. W., Rijnbeek, P. R., Van Zandt, M., Reich, C., Vashisht, R., Wu, Y., Duke, J., Hripcsak, G., Madigan, D., Shah, N. H., Ryan, P. B., Schuemie, M. J., Suchard, M. A. Shah, N. H., Rubin, D. L., Espinosa, I., Montgomery, K., Musen, M. A. Proton pump inhibitors (PPIs) are gastric acid-suppressing agents widely prescribed for the treatment of gastroesophageal reflux disease. View details for DOI 10.1210/me.2014-1120, View details for Web of Science ID 000346837000010. The result of our analysis is a network of 40,000 relationships between more than 200 entity types with clear semantics. Activity logs from health care professionals using online medical information resources are thus a valuable yet relatively untapped resource for large-scale medical surveillance.To analyze health care professionals' information-seeking behavior and assess the feasibility of measuring drug-safety alert response from the usage logs of an online medical information resource.Using two years (2011-2012) of usage logs from UpToDate, we measured the volume of searches related to medical conditions with significant burden in the United States, as well as the seasonal distribution of those searches.